Latest update: 17/05/2017

What can we offer you?

The Centrum voor Medische Genetica (Centre for Medical Genetics - CMG) at UZ Brussel offers different types of consultations for various phases of your life.
The consultations are usually multidisciplinary. This means you will not only see the genetics doctor of the CMG, but also a psychologist and/or a social health worker and/or (an)other health specialist(s) from UZ Brussel.

Practical

Whether you have been referred to us by your GP, gynaecologist or specialist, or whether you have contacted us independently, the Guide section tells you what to do for a consultation.

You should remember: 
  • that you always need to make an appointment via the CMG secretariat (see Contact), 
  • that both partners must register if you are coming for a consultation as a couple.

What is your question?

  • Our first child has a congenital disorder. Is this disorder hereditary? What is the risk if we have another child
  • We want to have children but my sister has two sons with a muscle disease. Is this disease hereditary? Do I face the same risks as my sister?
  • We have already had three miscarriages. Could there be a genetic cause?
  • My mother and grandfather became sick when they were about forty. My grandfather died at sixty after slowly losing his strength and his mental faculties. Is this an inherited disease?
  • I am pregnant and worried about the possibility of my baby having an inherited disorder. Is a prenatal ultrasound and genetic analysis recommended in this situation?

The CMG aims to help you find answers to questions such as these. You can consult us about any disorder you think might be hereditary.
If you want children and suspect your family has a hereditary problem, it is important you consult us before you try to get pregnant. This gives us the best chance to make sure you have a healthy pregnancy.


Initially we offer a consultation and guidance. In many cases, and with your written consent, genetic tests will be requested. Usually this is based on a simple blood test.
Depending on the (suspected) disorder this can be done at the CMG laboratories or tests can be carried out in collaboration with other laboratories in Belgium or abroad.

The aim of our services is to:
  • test whether a disorder or congenital disorder may be inherited.
  • in case of a rare disorder, try to reach a diagnosis and ascertain whether there is a risk that it will occur again.
  • use tests to predict whether you are at risk of having an inherited illness that manifests itself later in life (this is called late onset disease); 
  • work with you to consider your options if you want children and to support your decision by providing reliable information;
Finally, the CMG can also offer guidance via a consultation if you want a prenatal diagnosis during a pregnancy.


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The greatest limitation of genetic testing for patients is that it does not usually result in any treatment. Most chromosomal and genetic defects are incurable.
If a disorder has a biochemical cause, it can sometimes be treated.

Nevertheless a genetic diagnosis can sometimes help to recognise symptoms and treat them more effectively. This can lead to greater comfort and a better quality of life for patients. A correct diagnosis also allows a targeted follow-up plan with special attention for possible complications and may result in a more precise prognosis of the clinical picture.

For some patients it also offers an answer to whether a particular disorder occurring within a family is inherited and, if so, how likely it is that the patient himself or his/her descendants will inherit it. Sometimes this enables us to take preventative action.
For partners who want to have a child but have an inherited disorder, we can carry out a risk analysis (see Consultation before conception). Even if they already have a child that has inherited the condition, a diagnosis may be important when it comes to considering a possible future pregnancy.
That is because it is possible to carry out a PGD-analysis and/or a prenatal diagnosis. PGD treatment implicates the embryos being genetically tested in the context of IVF/ICSI treatment before being transferred to the uterus.

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