As soon as the CMG has all the necessary reports and samples and has identified the genetic abnormality, the development of the PGD test begins. The aim of this is to obtain a reliable genetic diagnosis on one or more cells from an embryo.
The time taken to develop the PGD test varies at present from a few weeks – for common indications – to eight months or longer – in rare or new indications.
How long does it take to develop a test?
The development of a PGD test can take a few weeks to a few months, depending on the disorder. Up till now, each disease has required a separate, often individualised test. In order to develop the test, we first need a genetic blood analysis of both prospective parents. With a monogenetic disorder we often also do a blood or DNA test of family members. We then explore how the wrong DNA code was transmitted and where precisely in the embryo’s DNA we have to search for the problem.
For some of the conditions we have already developed a PGD test with a number of markers. Therefore we will first examine whether you fit the existing test.
If that is the case, we can finish the test in a reasonably short period of time, in two to three months.
If this is not the case, then we have to develop a new test which can take some six to eight months.