Latest update: 22/05/2017

The preliminary process

PGD is specifically intended for people who are planning a family.

They are prospective parents – with or without a fertility problem
– who are at increased risk of passing on a hereditary disorder to their children.
Prospective parents who have reduced fertility or are infertile as the result of a genetic problem are obviously eligible for PGD as well.


Outpatient clinic appointments: good prepararion is half the battle

Each PGD treatment begins with two outpatient appointments (sometimes three):

  • with the geneticist, in combination with the PGD-coordinator
  • with the fertility gynaecologist, and
  • possibly with the psychologist.

If all assessments are positive the necessary blood samples are collected in order to develop a PGD test for the genetic analysis of the embryos.

Once the PGD test has been developed, we will invite you again to see:

 


During this consultation the doctor – a clinical geneticist (a medical expert in hereditary conditions) – will who checks that the conditions are eligible for developing a PGD test. She will also go through the available data regarding yourself, your partner and family members.

If you are eligible for PGD treatment you will also meet the PGD coordinator and/
or a social care nurse (see informative discussions with the counselor).

What can you do to help this consultation run efficiently?
  • Bring as much information as possible regarding your genetic disorder, such as the results of genetic tests and letters from doctors. 
  • Other information that you can provide us with or that we can assemble together:
    • the medical family tree of at least two generations, but preferably four: your own generation (including any brothers and sisters), that of your parents, that of any children already born to you, and possibly that of your grandparents;
    • the name and date of birth of family members with the genetic disorder;
    • any clinical and/or genetic reports of the family members who have the disorder.

Frequently asked question

Why do you need samples from our family members?

After the consultation we give you requests for blood tests, for yourself and possibly for family members.

  • Your blood samples are taken at UZ Brussel, as the analysis is usually also performed in-house.
  • Family members from whom we need a blood sample can visit their general practitioner or an external lab to get the sample taken The samples or results will then be forwarded to us.

In preparation for this consultation you can fill out an extensive questionnaire, which you can download – one for the woman, one for the man – from the CRG website www.crg.be.
If at all possible, we would like to receive the completed questionnaires in advance.

The fertility gynaecologist investigates the state of your fertility (both of you) and as such requests a number of (blood and other) tests.

In specific cases a psychological consultation is organised.
We do this for:

 

Following or during your first consultation with the geneticist (see before) you will meet the PGD coordinator and/or a social care nurse.
Shey/they will discuss the practical course of events with you and go through the PGD informed consent. Signing this consent is required to allow start of the treatment

Once the PGD test has been developed, we will invite you for another appointment with the geneticist and fertility gynaecologist.
This time there is also an important and lengthy conversation with the fertility counsellor scheduled.
This counsellor will go through the prescribed treatment schedule with you. The legal and practical aspects of the PGD treatment are discussed so that you are sufficiently informed to be able to sign the necessary contracts.
Because of the practical nature of this counselling session, it is best held as near as possible to the treatment itself.